منابع مشابه
Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells.
The gut is a major barrier against microbes and encloses various innate lymphoid cells (ILCs), including two subsets expressing the natural cytotoxicity receptor NKp46. A subset of NKp46(+) cells expresses retinoic acid receptor-related orphan receptor γt (RORγt) and produces IL-22, like lymphoid tissue inducer (LTi) cells. Other NKp46(+) cells lack RORγt and produce IFN-γ, like conventional Na...
متن کاملNKp46 regulates allergic responses
Natural killer (NK) cells are cytotoxic cells that are able to rapidly kill viruses, tumor cells, parasites, bacteria, and even cells considered "self". The activity of NK cells is controlled by a fine balance of inhibitory and activating signals mediated by a complex set of different receptors. However, the function of NK cells is not restricted only to the killing of target cells, NK cells al...
متن کاملTumor immunoediting by NKp46.
NK cells interact with a wide variety of hazardous cells including pathogen-infected and tumor cells. NKp46 is a specific NK killer receptor that recognizes various influenza hemagglutinins and unknown tumor ligands. It was recently shown that NKp46 plays a significant role in the in vivo eradication of tumor cells; however, the role played by NKp46 in vivo with regard to tumor development is s...
متن کاملExpression and function of NKp46 W32R: the human homologous protein of mouse NKp46 W32R (Noé)
Natural killer (NK) cells eradicate infected cells and tumors following the triggering of activating receptors, like the Natural Cytotoxicity Receptors (NCRs), which include NKp30, NKp44 and NKp46. NKp46 is the only NCR expressed in mice (mNKp46), and except for some Innate Lymphoid Cell (ILC) populations (ILC1/3 subsets), its expression is restricted to NK cells. Previously, a mouse named Noé ...
متن کاملPhysiology, Endocrinology, and Reproduction: Reproduction
conditions throughout the test. The hens were provided nutrients to meet the needs of all the hens based upon compilation of the breeder recommendations. The eggs from these strains were collected every 28 days from the previous 24 hrs production. Once collected the quality and compositional properties of the eggs such as pH, solids, whipping height, Haugh units and angel food cakes were evalua...
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ژورنال
عنوان ژورنال: Reproductive Immunology and Biology
سال: 2015
ISSN: 1881-607X,1881-7211
DOI: 10.3192/jsirib.30.1